Intrauterine Insemination or IUI is the direct injection of washed sperm into the uterine cavity (uterus). The sperm specimen is prepared using special preparation techniques.
The semen specimen must be produced preferably in our Andrology Laboratory, 90 minutes prior to the insemination. The insemination takes place in our outpatient clinic. Accurate timing is very important in maximizing the chance of pregnancy. Two inseminations are performed 24 hours apart.
At the time of the insemination, you will lie down on the examining table; a speculum will be inserted into your vagina (as if you were having a pap smear). The doctor or nurse will take the prepared (washed) sperm which has been placed in a syringe, and insert a small cannula (catheter tube) through your cervix into your uterus, near the fallopian tubes. The sperm will be passed very slowly into the uterus. This procedure takes approximately 5 - 10 minutes. You will be asked to remain lying flat for 5 minutes, and then you may get dressed and leave. We ask you to maintain a quiet and relaxed lifestyle for the next week or so, with no strenuous exercise. We ask you not to sit in a bath tub but rather take showers for the next 3 to 4 days. You may experience slight cramping after the insemination. This is normal. If your cramping is severe in nature, you may take plain Tylenol (without Codeine) or Ibuprofen (a mild anti-inflammatory). Do not take aspirin or any other medication without the doctor's or nurses advice. If you have any concerns, please call the clinic office.
The Progesterone suppositories will commence the morning following the second insemination, one in the morning and one at night inserted into your vagina. You will use the suppositories until you are confirmed pregnant in which case the doctor will continue your prescription for the first 13 weeks of your pregnancy. If your menstrual flow starts then you will discontinue the suppositories. If you are only spotting and do not have an actual flow, do not stop using the suppositories. If you find your prescription is getting low, please call the office and we will re-order your prescription for you so you do not run out. On cycle days 21 - 23 you will return to the doctor’s office for blood work to test your progesterone levels. Ultrasound is not required on this day.
A pregnancy test either by blood or urine is not performed until at least 16 days after the hCG injection is given. The reason for this is because the hormone that is detected in a pregnancy test is beta hCG. The injection that triggers your ovulation is hCG. If you were to perform a urine or a blood pregnancy test prior to the 14 days after the hCG injection, you will get a false positive result.
For those receiving the fertility medication injections and monitoring but not going to have artificial insemination, you will have intercourse the night of the hCG injection then the following 2 nights, then every other day thereafter for the next week.
The pregnancy rate for IUI is approximately 74% within 6 cycles of treatment.